Phillip Frost, physician and entrepreneur, built a biotechnology empire by identifying undervalued medical assets and scaling them through disciplined science-driven investing. As founder and chairman of OPKO Health, Frost assembled a diversified healthcare platform spanning diagnostics, pharmaceuticals, and medical technologies, often through strategic acquisitions and partnerships. Earlier in his career, he sold IVAX Corporation to Teva in a multibillion-dollar transaction, cementing his reputation as a leading dealmaker in life sciences. Known for a long-term approach to innovation and capital allocation, Frost remains a central figure in global healthcare entrepreneurship.

Mitchell Rales, cofounder of Danaher Corporation, is one of America’s most successful industrial builders, known for pairing disciplined capital allocation with a relentless focus on operational excellence. Alongside his brother Steven, Rales transformed Danaher from a small real estate company into a global science and technology conglomerate by pioneering the Danaher Business System, a management framework rooted in continuous improvement and lean manufacturing. After stepping back from day-to-day operations, Rales has remained an influential investor and philanthropist, supporting education, public policy, and cultural institutions through the Rales Foundation and Glenstone Museum.

Forrest Lee Preston, a self-made billionaire, founded Life Care Centers of America in 1970 and built it from a single facility in Cleveland, Tennessee, into one of the nation’s largest privately held networks of nursing homes, assisted-living, and retirement communities. As sole owner and CEO, he has overseen more than 200 locations across 27 states, employing over 30,000 people and serving tens of thousands of residents. Known for his hands-on control and aggressive expansion, Preston has navigated regulatory challenges and industry upheavals, cementing his reputation as a dominant force in the senior-care sector.

Cyrus Poonawalla is the chairman of Poonawalla Group, which includes the world's largest vaccine manufacturer by doses, Serum Institute of India. Known for his significant contributions to the pharmaceutical industry, his wealth and influence extend globally.

Thomas Frist Jr. is an American billionaire businessman and philanthropist. He is best known as the co-founder of Hospital Corporation of America (HCA), the world's largest private hospital operator. His business acumen and philanthropic efforts have left a significant mark on the healthcare industry and beyond.